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LITERATURE REVIEW

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  LITERATURE REVIEW Crude hypericum oblongifolium extract was studied for its anti-nociceptive, antipyretic and inflammatory properties by Naila Raziq et al [ 1 ] . They conducted hot plate tests and in vivo acetic acid-induced writhing experiments to determine the antinociceptive effects of 100,200 and 300mg/kgi.p. Yeast-induced hyperthermia and carrageenan-induced mouse paw edema were used to investigate the anti-inflammatory and anti-pyretic properties of methanol extracts, correspondingly. In numerous animal model, they discovered that methanol extract of hypericum oblongifolium had notable anti-pyretic, antinociceptive and anti-inflammatory properties. Ghulam Abbas et al [ 2 ] investigated the crude extracts of the two medicinally significant herbs hypericum perforatum and hypericum oblongifolium, for their possible cytotoxicity research, anti-lipid peroxidation, anti-glycation and antioxidant. They explore that aqueous n-Butanol fraction of hypericum perforatum demonstrate...